YDR126W

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Systematic name YDR126W
Gene name SWF1
Aliases PSL10
Feature type ORF, Verified
Coordinates Chr IV:703234..704244
Primary SGDID S000002533


Description of YDR126W: Palmitoyltransferase that acts on transmembrane proteins, including the SNAREs Snc1p, Syn8p, Tlg1p and likely all SNAREs; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion[1][2][3][4]




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References

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  1. Enyenihi AH and Saunders WS (2003) Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae. Genetics 163(1):47-54 SGD PMID 12586695
  2. Gonzalez Montoro A, et al. (2011) Specificity of transmembrane protein palmitoylation in yeast. PLoS One 6(2):e16969 SGD PMID 21383992
  3. Smotrys JE, et al. (2005) The vacuolar DHHC-CRD protein Pfa3p is a protein acyltransferase for Vac8p. J Cell Biol 170(7):1091-9 SGD PMID 16186255
  4. Valdez-Taubas J and Pelham H (2005) Swf1-dependent palmitoylation of the SNARE Tlg1 prevents its ubiquitination and degradation. EMBO J 24(14):2524-32 SGD PMID 15973437

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