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Systematic name YDR080W
Gene name VPS41
Aliases CVT8, FET2, SVL2, VAM2, VPL20
Feature type ORF, Verified
Coordinates Chr IV:604008..606986
Primary SGDID S000002487

Description of YDR080W: Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport[1][2][3]


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  1. Cowles CR, et al. (1997) Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component. EMBO J 16(10):2769-82 SGD PMID 9184222
  2. Nakamura N, et al. (1997) Vam2/Vps41p and Vam6/Vps39p are components of a protein complex on the vacuolar membranes and involved in the vacuolar assembly in the yeast Saccharomyces cerevisiae. J Biol Chem 272(17):11344-9 SGD PMID 9111041
  3. Seals DF, et al. (2000) A Ypt/Rab effector complex containing the Sec1 homolog Vps33p is required for homotypic vacuole fusion. Proc Natl Acad Sci U S A 97(17):9402-7 SGD PMID 10944212

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