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Systematic name YDR023W
Gene name SES1
Feature type ORF, Verified
Coordinates Chr IV:489508..490896
Primary SGDID S000002430

Description of YDR023W: Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p[1][2][3][4][5]


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  1. Gruic-Sovulj I, et al. (2002) tRNA-dependent amino acid discrimination by yeast seryl-tRNA synthetase. Eur J Biochem 269(21):5271-9 SGD PMID 12392560
  2. Lenhard B, et al. (1997) Defining the active site of yeast seryl-tRNA synthetase. Mutations in motif 2 loop residues affect tRNA-dependent amino acid recognition. J Biol Chem 272(2):1136-41 SGD PMID 8995413
  3. Lenhard B, et al. (1998) C-terminal truncation of yeast SerRS is toxic for Saccharomyces cerevisiae due to altered mechanism of substrate recognition. FEBS Lett 439(3):235-40 SGD PMID 9845329
  4. Rocak S, et al. (2002) Identifying Pex21p as a protein that specifically interacts with yeast seryl-tRNA synthetase. FEMS Microbiol Lett 214(1):101-6 SGD PMID 12204379
  5. Weygand-Durasevic I, et al. (1987) Cloning and characterization of the gene coding for cytoplasmic seryl-tRNA synthetase from Saccharomyces cerevisiae. Nucleic Acids Res 15(5):1887-904 SGD PMID 3031581

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