YDR016C
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| Systematic name | YDR016C |
| Gene name | DAD1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:478758..478474 |
| Primary SGDID | S000002423 |
Description of YDR016C: Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis[1][2][3][4]
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References
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- ↑ Enquist-Newman M, et al. (2001) Dad1p, third component of the Duo1p/Dam1p complex involved in kinetochore function and mitotic spindle integrity. Mol Biol Cell 12(9):2601-13 SGD PMID 11553702
- ↑ Miranda JJ, et al. (2005) The yeast DASH complex forms closed rings on microtubules. Nat Struct Mol Biol 12(2):138-43 SGD PMID 15640796
- ↑ Westermann S, et al. (2005) Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Mol Cell 17(2):277-90 SGD PMID 15664196
- ↑ Westermann S, et al. (2006) The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature 440(7083):565-9 SGD PMID 16415853
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