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Systematic name YDL213C
Gene name NOP6
Feature type ORF, Verified
Coordinates Chr IV:77966..77289
Primary SGDID S000002372

Description of YDL213C: rRNA-binding protein required for 40S ribosomal subunit biogenesis; contains an RNA recognition motif (RRM); hydrophilin essential to overcome the stress of the desiccation-rehydration process; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes[1][2][3][4]


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  1. Buchhaupt M, et al. (2007) Mutations in the nucleolar proteins Tma23 and Nop6 suppress the malfunction of the Nep1 protein. FEMS Yeast Res 7(6):771-81 SGD PMID 17425675
  2. Garay-Arroyo A, et al. (2000) Highly hydrophilic proteins in prokaryotes and eukaryotes are common during conditions of water deficit. J Biol Chem 275(8):5668-74 SGD PMID 10681550
  3. Garcia-Gomez JJ, et al. (2011) Nop6, a component of 90S pre-ribosomal particles, is required for 40S ribosomal subunit biogenesis in Saccharomyces cerevisiae. RNA Biol 8(1) SGD PMID 21282979
  4. Lopez-Martinez G, et al. (2012) The STF2p Hydrophilin from Saccharomyces cerevisiae Is Required for Dehydration Stress Tolerance. PLoS One 7(3):e33324 SGD PMID 22442684

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