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Systematic name YDL210W
Gene name UGA4
Feature type ORF, Verified
Coordinates Chr IV:84270..85985
Primary SGDID S000002369

Description of YDL210W: Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane[1][2][3][4]


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  1. Andre B, et al. (1993) Cloning and expression of the UGA4 gene coding for the inducible GABA-specific transport protein of Saccharomyces cerevisiae. Mol Gen Genet 237(1-2):17-25 SGD PMID 8455553
  2. Correa Garcia S, et al. (1997) Carbon and nitrogen sources regulate delta-aminolevulinic acid and gamma-aminobutyric acid transport in Saccharomyces cerevisiae. Int J Biochem Cell Biol 29(8-9):1097-101 SGD PMID 9416005
  3. Uemura T, et al. (2004) Uptake of GABA and putrescine by UGA4 on the vacuolar membrane in Saccharomyces cerevisiae. Biochem Biophys Res Commun 315(4):1082-7 SGD PMID 14985124
  4. Vissers S, et al. (1989) Positive and negative regulatory elements control the expression of the UGA4 gene coding for the inducible 4-aminobutyric-acid-specific permease in Saccharomyces cerevisiae. Eur J Biochem 181(2):357-61 SGD PMID 2653828

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