YDL174C

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Systematic name YDL174C
Gene name DLD1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:147589..145826
Primary SGDID S000002333


Description of YDL174C: D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane[1][2][3][4]




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References

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  1. Chelstowska A, et al. (1999) Signalling between mitochondria and the nucleus regulates the expression of a new D-lactate dehydrogenase activity in yeast. Yeast 15(13):1377-91 SGD PMID 10509019
  2. Lodi T and Ferrero I (1993) Isolation of the DLD gene of Saccharomyces cerevisiae encoding the mitochondrial enzyme D-lactate ferricytochrome c oxidoreductase. Mol Gen Genet 238(3):315-24 SGD PMID 8492799
  3. Lodi T, et al. (1999) Regulation of the Saccharomyces cerevisiae DLD1 gene encoding the mitochondrial protein D-lactate ferricytochrome c oxidoreductase by HAP1 and HAP2/3/4/5. Mol Gen Genet 262(4-5):623-32 SGD PMID 10628845
  4. Rojo EE, et al. (1998) Sorting of D-lactate dehydrogenase to the inner membrane of mitochondria. Analysis of topogenic signal and energetic requirements. J Biol Chem 273(14):8040-7 SGD PMID 9525904

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