YDL105W

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Systematic name YDL105W
Gene name NSE4
Aliases QRI2
Feature type ORF, Verified
Coordinates Chr IV:272389..273597
Primary SGDID S000002263


Description of YDL105W: Component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair[1][2][3][4]




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References

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  1. Bermudez-Lopez M, et al. (2010) The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. Nucleic Acids Res 38(19):6502-12 SGD PMID 20571088
  2. Hu B, et al. (2005) Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex. Mol Microbiol 55(6):1735-50 SGD PMID 15752197
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  4. Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 SGD PMID 15738391

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