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Systematic name YDL090C
Gene name RAM1
Aliases DPR1, FUS8, SCG2, SGP2, STE16
Feature type ORF, Verified
Coordinates Chr IV:296329..295034
Primary SGDID S000002248

Description of YDL090C: Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit[1][2][3][4][5]


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  1. Gomez R, et al. (1993) Purified yeast protein farnesyltransferase is structurally and functionally similar to its mammalian counterpart. Biochem J 289 ( Pt 1)():25-31 SGD PMID 8424764
  2. He B, et al. (1991) RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins. Proc Natl Acad Sci U S A 88(24):11373-7 SGD PMID 1763050
  3. Kohl NE, et al. (1991) Structural homology among mammalian and Saccharomyces cerevisiae isoprenyl-protein transferases. J Biol Chem 266(28):18884-8 SGD PMID 1918005
  4. Kurth DD, et al. (1997) Functional consequence of mutating conserved residues of the yeast farnesyl-protein transferase beta-subunit Ram1(Dpr1). Biochemistry 36(50):15932-9 SGD PMID 9398327
  5. Trueblood CE, et al. (1997) Substrate specificity determinants in the farnesyltransferase beta-subunit. Proc Natl Acad Sci U S A 94(20):10774-9 SGD PMID 9380709

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