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Systematic name YDL080C
Gene name THI3
Aliases KID1
Feature type ORF, Verified
Coordinates Chr IV:312471..310642
Primary SGDID S000002238

Description of YDL080C: Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis[1][2][3][4]


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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in nitrogen limited chemostat cultures versus nitrogen excess. [5] [6]



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  1. Dickinson JR, et al. (2000) An investigation of the metabolism of isoleucine to active Amyl alcohol in Saccharomyces cerevisiae. J Biol Chem 275(15):10937-42 SGD PMID 10753893
  2. Dickinson JR, et al. (2003) The catabolism of amino acids to long chain and complex alcohols in Saccharomyces cerevisiae. J Biol Chem 278(10):8028-34 SGD PMID 12499363
  3. Nishimura H, et al. (1992) A positive regulatory gene, THI3, is required for thiamine metabolism in Saccharomyces cerevisiae. J Bacteriol 174(14):4701-6 SGD PMID 1624458
  4. Nosaka K, et al. (1993) Isolation and characterization of a thiamin pyrophosphokinase gene, THI80, from Saccharomyces cerevisiae. J Biol Chem 268(23):17440-7 SGD PMID 8394343
  5. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. submitted by Viktor Boer on 2003-07-25

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