YDL051W

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Systematic name YDL051W
Gene name LHP1
Aliases LAH1, YLA1
Feature type ORF, Verified
Coordinates Chr IV:363952..364779
Primary SGDID S000002209


Description of YDL051W: RNA binding protein required for maturation of tRNA and U6 snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen[1][2][3]




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References

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  1. Lin-Marq N and Clarkson SG (1995) A yeast RNA binding protein that resembles the human autoantigen La. J Mol Biol 245(2):81-5 SGD PMID 7799435
  2. Pannone BK, et al. (1998) A role for the yeast La protein in U6 snRNP assembly: evidence that the La protein is a molecular chaperone for RNA polymerase III transcripts. EMBO J 17(24):7442-53 SGD PMID 9857199
  3. Yoo CJ and Wolin SL (1997) The yeast La protein is required for the 3' endonucleolytic cleavage that matures tRNA precursors. Cell 89(3):393-402 SGD PMID 9150139

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