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Systematic name YDL035C
Gene name GPR1
Feature type ORF, Verified
Coordinates Chr IV:392057..389172
Primary SGDID S000002193

Description of YDL035C: Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis[1][2][3][4][5]


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  1. Ansari K, et al. (1999) Phospholipase C binds to the receptor-like GPR1 protein and controls pseudohyphal differentiation in Saccharomyces cerevisiae. J Biol Chem 274(42):30052-8 SGD PMID 10514491
  2. Kraakman L, et al. (1999) A Saccharomyces cerevisiae G-protein coupled receptor, Gpr1, is specifically required for glucose activation of the cAMP pathway during the transition to growth on glucose. Mol Microbiol 32(5):1002-12 SGD PMID 10361302
  3. Pan X and Heitman J (1999) Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol Cell Biol 19(7):4874-87 SGD PMID 10373537
  4. Xue Y, et al. (1998) GPR1 encodes a putative G protein-coupled receptor that associates with the Gpa2p Galpha subunit and functions in a Ras-independent pathway. EMBO J 17(7):1996-2007 SGD PMID 9524122
  5. Yun CW, et al. (1997) G-protein coupled receptor from yeast Saccharomyces cerevisiae. Biochem Biophys Res Commun 240(2):287-92 SGD PMID 9388468

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