YCR077C

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Systematic name YCR077C
Gene name PAT1
Aliases MRT1
Feature type ORF, Verified
Coordinates Chr III:252628..250238
Primary SGDID S000000673


Description of YCR077C: Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p[1][2][3][4]




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References

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  1. Bonnerot C, et al. (2000) The two proteins Pat1p (Mrt1p) and Spb8p interact in vivo, are required for mRNA decay, and are functionally linked to Pab1p. Mol Cell Biol 20(16):5939-46 SGD PMID 10913177
  2. Noueiry AO, et al. (2003) Yeast Lsm1p-7p/Pat1p deadenylation-dependent mRNA-decapping factors are required for brome mosaic virus genomic RNA translation. Mol Cell Biol 23(12):4094-106 SGD PMID 12773554
  3. Wang X, et al. (1996) Pat1: a topoisomerase II-associated protein required for faithful chromosome transmission in Saccharomyces cerevisiae. Nucleic Acids Res 24(23):4791-7 SGD PMID 8972867
  4. Wang X, et al. (1999) The topoisomerase II-associated protein, Pat1p, is required for maintenance of rDNA locus stability in Saccharomyces cerevisiae. Mol Gen Genet 261(4-5):831-40 SGD PMID 10394921

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