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Systematic name YCR073C
Gene name SSK22
Feature type ORF, Verified
Coordinates Chr III:246583..242588
Primary SGDID S000000669

Description of YCR073C: MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; functionally redundant with, and homologous to, Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p[1][2]


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  1. Posas F and Saito H (1998) Activation of the yeast SSK2 MAP kinase kinase kinase by the SSK1 two-component response regulator. EMBO J 17(5):1385-94 SGD PMID 9482735
  2. Tatebayashi K, et al. (2003) A docking site determining specificity of Pbs2 MAPKK for Ssk2/Ssk22 MAPKKKs in the yeast HOG pathway. EMBO J 22(14):3624-34 SGD PMID 12853477

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