YCR031C
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| Systematic name | YCR031C |
| Gene name | RPS14A |
| Aliases | CRY1, RPL59 |
| Feature type | ORF, Verified |
| Coordinates | Chr III:178220..177500 |
| Primary SGDID | S000000627 |
Description of YCR031C: Protein component of the small (40S) ribosomal subunit; required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; homologous to mammalian ribosomal protein S14 and bacterial S11; RPS14A has a paralog, RPS14B, that arose from the whole genome duplication[1][2][3][4][5][6]
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References
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- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Jakovljevic J, et al. (2004) The carboxy-terminal extension of yeast ribosomal protein S14 is necessary for maturation of 43S preribosomes. Mol Cell 14(3):331-42 SGD PMID 15125836
- ↑ Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () SGD PMID 22884264
- ↑ Larkin JC, et al. (1987) Structure and expression of the Saccharomyces cerevisiae CRY1 gene: a highly conserved ribosomal protein gene. Mol Cell Biol 7(5):1764-75 SGD PMID 3037334
- ↑ Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 SGD PMID 12490706
- ↑ Moritz M, et al. (1990) Depletion of yeast ribosomal proteins L16 or rp59 disrupts ribosome assembly. J Cell Biol 111(6 Pt 1):2261-74 SGD PMID 2277060
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