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Systematic name YCR005C
Gene name CIT2
Feature type ORF, Verified
Coordinates Chr III:122328..120946
Primary SGDID S000000598

Description of YCR005C: Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors[1][2][3]


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  1. Kim KS, et al. (1986) Saccharomyces cerevisiae contains two functional citrate synthase genes. Mol Cell Biol 6(6):1936-42 SGD PMID 3023912
  2. Lewin AS, et al. (1990) Citrate synthase encoded by the CIT2 gene of Saccharomyces cerevisiae is peroxisomal. Mol Cell Biol 10(4):1399-405 SGD PMID 2181273
  3. Liao X and Butow RA (1993) RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72(1):61-71 SGD PMID 8422683

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