YCL040W

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Systematic name YCL040W
Gene name GLK1
Aliases HOR3
Feature type ORF, Verified
Coordinates Chr III:50838..52340
Primary SGDID S000000545


Description of YCL040W: Glucokinase; catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources; GLK1 has a paralog, EMI2, that arose from the whole genome duplication[1][2][3]




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References

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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Herrero P, et al. (1995) Transcriptional regulation of the Saccharomyces cerevisiae HXK1, HXK2 and GLK1 genes. Yeast 11(2):137-44 SGD PMID 7732723
  3. Rodriguez A, et al. (2001) The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae. Biochem J 355(Pt 3):625-31 SGD PMID 11311123

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