YCL038C

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Systematic name YCL038C
Gene name ATG22
Aliases AUT4
Feature type ORF, Verified
Coordinates Chr III:56527..54941
Primary SGDID S000000543


Description of YCL038C: Vacuolar integral membrane protein required for efflux of amino acids during autophagic body breakdown in the vacuole; null mutation causes a gradual loss of viability during starvation[1][2][3]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [4] [5]





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References

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  1. Suriapranata I, et al. (2000) The breakdown of autophagic vesicles inside the vacuole depends on Aut4p. J Cell Sci 113 ( Pt 22):4025-33 SGD PMID 11058089
  2. Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160
  3. Yang Z, et al. (2006) Atg22 recycles amino acids to link the degradative and recycling functions of autophagy. Mol Biol Cell 17(12):5094-104 SGD PMID 17021250
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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