YCL010C

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Systematic name YCL010C
Gene name SGF29
Aliases
Feature type ORF, Verified
Coordinates Chr III:104350..103571
Primary SGDID S000000516


Description of YCL010C: Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes; HAT/Core module also contains Gcn5p, Ngg1p, and Ada2p; binds methylated histone H3K4; involved in transcriptional regulation through SAGA and TBP recruitment to target promoters and H3 acetylation[1][2][3][4]




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References

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  1. Bian C, et al. (2011) Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.LID - 10.1038/emboj.2011.193 [doi] EMBO J () SGD PMID 21685874
  2. Lee KK, et al. (2011) Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes. Mol Syst Biol 7():503 SGD PMID 21734642
  3. Sanders SL, et al. (2002) Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry. Mol Cell Biol 22(13):4723-38 SGD PMID 12052880
  4. Shukla A, et al. (2012) Sgf29p facilitates the recruitment of TATA box binding protein but does not alter SAGA's global structural integrity in vivo. Biochemistry 51(2):706-14 SGD PMID 22224423

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