From SGD-Wiki
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YBR218C
Gene name PYC2
Feature type ORF, Verified
Coordinates Chr II:662249..658707
Primary SGDID S000000422

Description of YBR218C: Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis[1][2][3]


Community Commentary

About Community Commentary. Please share your knowledge!



See Help:References on how to add references

  1. Brewster NK, et al. (1994) Regulation of pyruvate carboxylase isozyme (PYC1, PYC2) gene expression in Saccharomyces cerevisiae during fermentative and nonfermentative growth. Arch Biochem Biophys 311(1):62-71 SGD PMID 8185321
  2. Foury F (1997) Human genetic diseases: a cross-talk between man and yeast. Gene 195(1):1-10 SGD PMID 9300813
  3. Walker ME, et al. (1991) Yeast pyruvate carboxylase: identification of two genes encoding isoenzymes. Biochem Biophys Res Commun 176(3):1210-7 SGD PMID 2039506

See Help:Categories on how to add the wiki page for this gene to a Category </protect>