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Systematic name YBR201W
Gene name DER1
Feature type ORF, Verified
Coordinates Chr II:623576..624211
Primary SGDID S000000405

Description of YBR201W: Endoplasmic reticulum membrane protein, required for ER-associated protein degradation of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p[1][2][3]


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  1. Hitt R and Wolf DH (2004) Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins. FEMS Yeast Res 4(7):721-9 SGD PMID 15093775
  2. Knop M, et al. (1996) Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast. EMBO J 15(4):753-63 SGD PMID 8631297
  3. Sommer T and Wolf DH (1997) Endoplasmic reticulum degradation: reverse protein flow of no return. FASEB J 11(14):1227-33 SGD PMID 9409541

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