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Systematic name YBR163W
Gene name EXO5
Aliases DEM1
Feature type ORF, Verified
Coordinates Chr II:565723..567480
Primary SGDID S000000367

Description of YBR163W: Mitochondrial 5'-3' exonuclease and sliding exonuclease, required for mitochondrial genome maintenance; distantly related to the RecB nuclease domain of bacterial RecBCD recombinases; may be regulated by the transcription factor Ace2[1][2][3][4]


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  1. Burgers PM, et al. (2010) Yeast exonuclease 5 is essential for mitochondrial genome maintenance. Mol Cell Biol 30(6):1457-66 SGD PMID 20086101
  2. Entian KD, et al. (1999) Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach. Mol Gen Genet 262(4-5):683-702 SGD PMID 10628851
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  4. Sun W, et al. (2007) Detection of eQTL modules mediated by activity levels of transcription factors. Bioinformatics 23(17):2290-7 SGD PMID 17599927

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