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Systematic name YBR147W
Gene name RTC2
Aliases RRT11
Feature type ORF, Verified
Coordinates Chr II:536575..537465
Primary SGDID S000000351

Description of YBR147W: Protein of unknown function; mutant produces large lipid droplets, is resistant to fluconazole, has decreased levels of rDNA transcription, growth defects on minimal media, and suppresses cdc13-1; detected in highly purified mitochondria; similar to a G-protein coupled receptor from S. pombe[1][2][3][4][5][6][7]


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  1. Addinall SG, et al. (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66 SGD PMID 18845848
  2. Anderson JB, et al. (2003) Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae. Genetics 163(4):1287-98 SGD PMID 12702675
  3. Fei W, et al. (2011) A role for phosphatidic Acid in the formation of supersized lipid droplets. PLoS Genet 7(7):e1002201 SGD PMID 21829381
  4. Hontz RD, et al. (2009) Genetic Identification of Factors That Modulate Ribosomal DNA Transcription in Saccharomyces cerevisiae. Genetics 182(1):105-19 SGD PMID 19270272
  5. Jimenez-Marti E and Del Olmo ML (2008) Addition of ammonia or amino acids to a nitrogen-depleted medium affects gene expression patterns in yeast cells during alcoholic fermentation. FEMS Yeast Res 8(2):245-56 SGD PMID 17986253
  6. Reinders J, et al. (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54 SGD PMID 16823961
  7. Van Dijck P (2009) Nutrient sensing G protein-coupled receptors: interesting targets for antifungals? Med Mycol 47(7):671-80 SGD PMID 19888799

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