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Systematic name YBR133C
Gene name HSL7
Feature type ORF, Verified
Coordinates Chr II:504287..501804
Primary SGDID S000000337

Description of YBR133C: Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p[1][2][3][4][5][6]


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  1. Cid VJ, et al. (2001) Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle. Mol Biol Cell 12(6):1645-69 SGD PMID 11408575
  2. Lee JH, et al. (2000) Hsl7p, the yeast homologue of human JBP1, is a protein methyltransferase. Biochem Biophys Res Commun 274(1):105-11 SGD PMID 10903903
  3. Longtine MS, et al. (2000) Septin-dependent assembly of a cell cycle-regulatory module in Saccharomyces cerevisiae. Mol Cell Biol 20(11):4049-61 SGD PMID 10805747
  4. McMillan JN, et al. (1999) The morphogenesis checkpoint in Saccharomyces cerevisiae: cell cycle control of Swe1p degradation by Hsl1p and Hsl7p. Mol Cell Biol 19(10):6929-39 SGD PMID 10490630
  5. Sakchaisri K, et al. (2004) Coupling morphogenesis to mitotic entry. Proc Natl Acad Sci U S A 101(12):4124-9 SGD PMID 15037762
  6. Shulewitz MJ, et al. (1999) Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae. Mol Cell Biol 19(10):7123-37 SGD PMID 10490648

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