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Systematic name YBR132C
Gene name AGP2
Feature type ORF, Verified
Coordinates Chr II:501442..499652
Primary SGDID S000000336

Description of YBR132C: High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease[1][2][3][4]


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  1. Aouida M, et al. (2005) AGP2 encodes the major permease for high affinity polyamine import in Saccharomyces cerevisiae. J Biol Chem 280(25):24267-76 SGD PMID 15855155
  2. Lee J, et al. (2002) Carnitine uptake by AGP2 in yeast Saccharomyces cerevisiae is dependent on Hog1 MAP kinase pathway. Mol Cells 13(3):407-12 SGD PMID 12132580
  3. Schreve JL and Garrett JM (2004) Yeast Agp2p and Agp3p function as amino acid permeases in poor nutrient conditions. Biochem Biophys Res Commun 313(3):745-51 SGD PMID 14697254
  4. van Roermund CW, et al. (1999) Molecular characterization of carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria in Saccharomyces cerevisiae and identification of a plasma membrane carnitine transporter, Agp2p. EMBO J 18(21):5843-52 SGD PMID 10545096

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