YBR092C

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Systematic name YBR092C
Gene name PHO3
Aliases phoC
Feature type ORF, Verified
Coordinates Chr II:429101..427698
Primary SGDID S000000296


Description of YBR092C: Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin[1][2][3][4][5]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [6] [7]





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References

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  1. Bajwa W, et al. (1984) Structural analysis of the two tandemly repeated acid phosphatase genes in yeast. Nucleic Acids Res 12(20):7721-39 SGD PMID 6093051
  2. Nosaka K, et al. (1989) A possible role for acid phosphatase with thiamin-binding activity encoded by PHO3 in yeast. FEMS Microbiol Lett 51(1):55-9 SGD PMID 2676709
  3. Nosaka K, et al. (1989) Identity of soluble thiamine-binding protein with thiamine repressible acid phosphatase in Saccharomyces cerevisiae. Yeast 5 Spec No:S447-51 SGD PMID 2665373
  4. Praetorius-Ibba M, et al. (1997) Homologous recombination partly restores the secretion defect of underglycosylated acid phosphatase in yeast. Curr Genet 32(3):190-6 SGD PMID 9339343
  5. Toh-e A, et al. (1981) Structure and function of the PHO82-pho4 locus controlling the synthesis of repressible acid phosphatase of Saccharomyces cerevisiae. J Bacteriol 145(1):221-32 SGD PMID 7007314
  6. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  7. submitted by Viktor Boer on 2003-07-25

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