YBR077C

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Systematic name YBR077C
Gene name SLM4
Aliases EGO3, GSE1, NIR1
Feature type ORF, Verified
Coordinates Chr II:392293..391805
Primary SGDID S000000281


Description of YBR077C: Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; gene exhibits synthetic genetic interaction with MSS4[1][2][3][4]




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References

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  1. Audhya A, et al. (2004) Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. EMBO J 23(19):3747-57 SGD PMID 15372071
  2. Dubouloz F, et al. (2005) The TOR and EGO protein complexes orchestrate microautophagy in yeast. Mol Cell 19(1):15-26 SGD PMID 15989961
  3. Gao M and Kaiser CA (2006) A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast. Nat Cell Biol 8(7):657-67 SGD PMID 16732272
  4. Huang J, et al. (2004) Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips. Proc Natl Acad Sci U S A 101(47):16594-9 SGD PMID 15539461

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