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Systematic name YBL061C
Gene name SKT5
Aliases CAL2, CHS4, CSD4
Feature type ORF, Verified
Coordinates Chr II:107406..105316
Primary SGDID S000000157

Description of YBL061C: Activator of Chs3p (chitin synthase III) during vegetative growth; recruits Chs3p to the bud neck via interaction with Bni4p; SKT5 has a paralog, SHC1, that arose from the whole genome duplication[1][2][3][4][5]


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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Kozubowski L, et al. (2003) A Bni4-Glc7 phosphatase complex that recruits chitin synthase to the site of bud emergence. Mol Biol Cell 14(1):26-39 SGD PMID 12529424
  3. Ono N, et al. (2000) The yeast Chs4 protein stimulates the trypsin-sensitive activity of chitin synthase 3 through an apparent protein-protein interaction. Microbiology 146 ( Pt 2):385-91 SGD PMID 10708377
  4. Sanz M, et al. (2002) Control of chitin synthesis through Shc1p, a functional homologue of Chs4p specifically induced during sporulation. Mol Microbiol 43(5):1183-95 SGD PMID 11918806
  5. Trilla JA, et al. (1997) Characterization of CHS4 (CAL2), a gene of Saccharomyces cerevisiae involved in chitin biosynthesis and allelic to SKT5 and CSD4. Yeast 13(9):795-807 SGD PMID 9234668

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