YBL058W

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Systematic name YBL058W
Gene name SHP1
Aliases UBX1
Feature type ORF, Verified
Coordinates Chr II:111437..112708
Primary SGDID S000000154


Description of YBL058W: UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate[1][2][3]




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References

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  1. Schuberth C, et al. (2004) Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation. EMBO Rep 5(8):818-24 SGD PMID 15258615
  2. Tong AH, et al. (2004) Global mapping of the yeast genetic interaction network. Science 303(5659):808-13 SGD PMID 14764870
  3. Zhang S, et al. (1995) The Saccharomyces SHP1 gene, which encodes a regulator of phosphoprotein phosphatase 1 with differential effects on glycogen metabolism, meiotic differentiation, and mitotic cell cycle progression. Mol Cell Biol 15(4):2037-50 SGD PMID 7891699

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