YBL057C
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| Systematic name | YBL057C |
| Gene name | PTH2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:113427..112801 |
| Primary SGDID | S000000153 |
Description of YBL057C: One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth[1][2][3][4]
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References
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- ↑ Fromant M, et al. (2003) Peptidyl-tRNA hydrolase from Sulfolobus solfataricus. Nucleic Acids Res 31(12):3227-35 SGD PMID 12799450
- ↑ Ishii T, et al. (2006) Yeast Pth2 is a UBL domain-binding protein that participates in the ubiquitin-proteasome pathway. EMBO J 25(23):5492-503 SGD PMID 17082762
- ↑ Rosas-Sandoval G, et al. (2002) Orthologs of a novel archaeal and of the bacterial peptidyl-tRNA hydrolase are nonessential in yeast. Proc Natl Acad Sci U S A 99(26):16707-12 SGD PMID 12475929
- ↑ Sickmann A, et al. (2003) The proteome of Saccharomyces cerevisiae mitochondria. Proc Natl Acad Sci U S A 100(23):13207-12 SGD PMID 14576278
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