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Systematic name YBL040C
Gene name ERD2
Feature type ORF, Verified
Coordinates Chr II:142868..142112
Primary SGDID S000000136

Description of YBL040C: HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins[1][2][3][4]


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  1. Beh CT and Rose MD (1995) Two redundant systems maintain levels of resident proteins within the yeast endoplasmic reticulum. Proc Natl Acad Sci U S A 92(21):9820-3 SGD PMID 7568225
  2. Hardwick KG, et al. (1990) ERD1, a yeast gene required for the retention of luminal endoplasmic reticulum proteins, affects glycoprotein processing in the Golgi apparatus. EMBO J 9(3):623-30 SGD PMID 2178921
  3. Lewis MJ and Pelham HR (1990) A human homologue of the yeast HDEL receptor. Nature 348(6297):162-3 SGD PMID 2172835
  4. Semenza JC, et al. (1990) ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway. Cell 61(7):1349-57 SGD PMID 2194670

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