YBL033C

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Systematic name YBL033C
Gene name RIB1
Aliases
Feature type ORF, Verified
Coordinates Chr II:159693..158656
Primary SGDID S000000129


Description of YBL033C: GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway[1][2][3]




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Community Commentary

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RIB1 null mutants are auxotrophic for riboflavin so this must be added to the growth media for strain viability (Angela Chu, personal communication).



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References

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  1. Buitrago MJ, et al. (1993) Mapping of the RIB1 and RIB7 genes involved in the biosynthesis of riboflavin in Saccharomyces cerevisiae. Yeast 9(10):1099-102 SGD PMID 8256517
  2. Oltmanns O and Bacher A (1972) Biosynthesis of riboflavine in Saccharomyces cerevisiae: the role of genes rib 1 and rib 7. J Bacteriol 110(3):818-22 SGD PMID 4555411
  3. Richter G, et al. (1997) Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis. J Bacteriol 179(6):2022-8 SGD PMID 9068650

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References

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