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Systematic name YBL022C
Gene name PIM1
Aliases LON1
Feature type ORF, Verified
Coordinates Chr II:181275..177874
Primary SGDID S000000118

Description of YBL022C: ATP-dependent Lon protease, involved in degradation of misfolded proteins in mitochondria; required for biogenesis and maintenance of mitochondria[1][2][3]


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  1. Suzuki CK, et al. (1994) Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration. Science 264(5156):273-6 SGD PMID 8146662
  2. Van Dyck L, et al. (1994) PIM1 encodes a mitochondrial ATP-dependent protease that is required for mitochondrial function in the yeast Saccharomyces cerevisiae. J Biol Chem 269(1):238-42 SGD PMID 8276800
  3. Wagner I, et al. (1994) Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria. EMBO J 13(21):5135-45 SGD PMID 7957078

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