YAL038W

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Systematic name YAL038W
Gene name CDC19
Aliases PYK1
Feature type ORF, Verified
Coordinates Chr I:71786..73288
Primary SGDID S000000036


Description of YAL038W: Pyruvate kinase; functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; CDC19 has a paralog, PYK2, that arose from the whole genome duplication[1][2]




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References

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  1. Jump up Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Jump up Pearce AK, et al. (2001) Pyruvate kinase (Pyk1) levels influence both the rate and direction of carbon flux in yeast under fermentative conditions. Microbiology 147(Pt 2):391-401 SGD PMID 11158356

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