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Systematic name YAL021C
Gene name CCR4
Aliases FUN27, NUT21
Feature type ORF, Verified
Coordinates Chr I:113359..110846
Primary SGDID S000000019

Description of YAL021C: Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening[1][2][3]


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  1. Denis CL and Malvar T (1990) The CCR4 gene from Saccharomyces cerevisiae is required for both nonfermentative and spt-mediated gene expression. Genetics 124(2):283-91 SGD PMID 2407614
  2. Liu HY, et al. (1998) The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively. EMBO J 17(4):1096-106 SGD PMID 9463387
  3. Tucker M, et al. (2001) The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell 104(3):377-86 SGD PMID 11239395

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