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Systematic name YAL011W
Gene name SWC3
Aliases SWC1
Feature type ORF, Verified
Coordinates Chr I:132199..134076
Primary SGDID S000000009

Description of YAL011W: Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae[1][2][3]


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  1. Krogan NJ, et al. (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76 SGD PMID 14690608
  2. Mizuguchi G, et al. (2004) ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303(5656):343-8 SGD PMID 14645854
  3. Wright R, et al. (2003) Parallel analysis of tagged deletion mutants efficiently identifies genes involved in endoplasmic reticulum biogenesis. Yeast 20(10):881-92 SGD PMID 12868057

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