YDR416W
(Redirected from SYF1)
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| Systematic name | YDR416W |
| Gene name | SYF1 |
| Aliases | NTC90 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1298432..1301011 |
| Primary SGDID | S000002824 |
Description of YDR416W: Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; null mutant has splicing defect and arrests in G2/M; homologs in human and C. elegans[1][2][3]
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References
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- ↑ Ben-Yehuda S, et al. (2000) Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae. Genetics 156(4):1503-17 SGD PMID 11102353
- ↑ Chen CH, et al. (2006) Functional links between the Prp19-associated complex, U4/U6 biogenesis, and spliceosome recycling. RNA 12(5):765-74 SGD PMID 16540691
- ↑ Russell CS, et al. (2000) Functional analyses of interacting factors involved in both pre-mRNA splicing and cell cycle progression in Saccharomyces cerevisiae. RNA 6(11):1565-72 SGD PMID 11105756
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