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Systematic name NME1
Gene name NME1
Aliases RRP2
Feature type snoRNA
Coordinates Chr XIV:585587..585926
Primary SGDID S000007436

Description of NME1: RNA component of RNase MRP, which cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; human ortholog is implicated in cartilage-hair hypoplasia (CHH)[1][2][3][4]


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  1. Chu S, et al. (1994) The RNA of RNase MRP is required for normal processing of ribosomal RNA. Proc Natl Acad Sci U S A 91(2):659-63 SGD PMID 8290578
  2. Gill T, et al. (2006) A specialized processing body that is temporally and asymmetrically regulated during the cell cycle in Saccharomyces cerevisiae. J Cell Biol 173(1):35-45 SGD PMID 16585272
  3. Houser-Scott F, et al. (2002) Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P. Proc Natl Acad Sci U S A 99(5):2684-9 SGD PMID 11880623
  4. Martin AN and Li Y (2007) RNase MRP RNA and human genetic diseases. Cell Res 17(3):219-26 SGD PMID 17189938

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