YCR081W
(Redirected from MED12)
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| Systematic name | YCR081W |
| Gene name | SRB8 |
| Aliases | GIG1, MED12, NUT6, SSN5, YCR080W |
| Feature type | ORF, Verified |
| Coordinates | Chr III:254371..258654 |
| Primary SGDID | S000000677 |
Description of YCR081W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression[1][2][3]
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References
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- ↑ Balciunas D and Ronne H (1995) Three subunits of the RNA polymerase II mediator complex are involved in glucose repression. Nucleic Acids Res 23(21):4421-5 SGD PMID 7501465
- ↑ Hengartner CJ, et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9(8):897-910 SGD PMID 7774808
- ↑ Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
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