YHR200W
(Redirected from MCB1)
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| Systematic name | YHR200W |
| Gene name | RPN10 |
| Aliases | MCB1, SUN1 |
| Feature type | ORF, Verified |
| Coordinates | Chr VIII:499079..499885 |
| Primary SGDID | S000001243 |
Description of YHR200W: Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein[1][2][3][4]
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References
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- ↑ Deveraux Q, et al. (1994) A 26 S protease subunit that binds ubiquitin conjugates. J Biol Chem 269(10):7059-61 SGD PMID 8125911
- ↑ Elsasser S, et al. (2002) Proteasome subunit Rpn1 binds ubiquitin-like protein domains. Nat Cell Biol 4(9):725-30 SGD PMID 12198498
- ↑ Finley D, et al. (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5 SGD PMID 9697412
- ↑ Glickman MH, et al. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94(5):615-23 SGD PMID 9741626
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