Genome Compiler

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Genome Compiler is an all-in-one platform for life scientists in the genetic engineering, molecular biology and synthetic biology fields, which provides a comprehensive tool for:

  • DNA design and visualization
  • Data management
  • Collaboration platform
  • Seamless DNA ordering

Genome Compiler is free for academia users and is available online and in a downloadable version so you can easily access your data on Genome Compiler from anywhere you are. The software supports Windows and Mac. In addition, the software supports common file formats such as: FASTA, Vector NTI, SnapGene, Geneious, Clone Manager, Serial Cloner, Plasma DNA, ApE, DNAStar, etc.


  • Cloning - design your cloning experiments by the intuitive cloning wizards. The software supports Restriction Ligation (for digest and ligate using restriction enzymes or PCR) and Gibson Assembly methods.
  • Sequence alignment - simultaneously align your chromatogram files (.ab1, .scf) against your template sequence, locate and correct errors instantly.
  • Sequence annotation - seamlessly auto-annotate your sequences and FASTA files. You can use our extensive library or add your own.
  • Primer design - design primers automatically or manually. Using the software you can also create a Primer Library in order manage your inventory and automatically attach complementary primers to your projects.
  • RBS Calculator - predict and control the protein expression rate in bacteria by this tool by the Salis lab, which is embedded into Genome Compiler.

More Tools

  • Full genome visualization
  • Combinatorial design
  • Virtual digest and gel electrophoresis results simulation
  • Back translation and codon optimization
  • ORF detection
  • Optimize Codon Usage

Embedded Databases

Inside Genome Compiler Materials Box you'll find thousands of sequences, plasmids and parts from different repositories:

In addition, there is an auto annotation library, containing the Plasmapper database of parts, including hundreds of commonly used coding sequences, promoters and terminators and more, which can be “Blasted” against to auto annotate your sequences. It is also possible to query the NCBI database from within Genome Compiler and then instantly import your data into the Materials Box directly from Genome Compiler.

Collaboration Platform

Using Genome Compiler, you can work efficiently with your friends and colleagues at the lab. You can share your primers, sequences and projects with others and let them edit and add their comments. Every change made to the data you share is trackable and can be easily accessed.

Learning How to Use the Software

Using Genome Compiler is simple and intuitive, but these tools will help you become a Genome Compiler expert faster:

You can also leave us a feedback at any time or send your requests for further enhancements or features.

See Also