YBL016W
(Redirected from FUS3)
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| Systematic name | YBL016W |
| Gene name | FUS3 |
| Aliases | DAC2 |
| Feature type | ORF, Verified |
| Coordinates | Chr II:192451..193512 |
| Primary SGDID | S000000112 |
Description of YBL016W: Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation[1][2][3][4][5][6]
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References
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- ↑ Bao MZ, et al. (2004) Pheromone-dependent destruction of the Tec1 transcription factor is required for MAP kinase signaling specificity in yeast. Cell 119(7):991-1000 SGD PMID 15620357
- ↑ Breitkreutz A and Tyers M (2002) MAPK signaling specificity: it takes two to tango. Trends Cell Biol 12(6):254-7 SGD PMID 12074884
- ↑ Elion EA, et al. (1993) FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1. Mol Biol Cell 4(5):495-510 SGD PMID 8334305
- ↑ Garrison TR, et al. (1999) Feedback phosphorylation of an RGS protein by MAP kinase in yeast. J Biol Chem 274(51):36387-91 SGD PMID 10593933
- ↑ Matheos D, et al. (2004) Pheromone-induced polarization is dependent on the Fus3p MAPK acting through the formin Bni1p. J Cell Biol 165(1):99-109 SGD PMID 15067022
- ↑ Ptashne M and Gann A (2003) Signal transduction. Imposing specificity on kinases. Science 299(5609):1025-7 SGD PMID 12586931
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