YKL048C
(Redirected from ELM1)
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| Systematic name | YKL048C |
| Gene name | ELM1 |
| Aliases | LDB9 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:349136..347214 |
| Primary SGDID | S000001531 |
Description of YKL048C: Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring[1][2][3][4][5]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [6] [7]
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References
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- ↑ Bouquin N, et al. (2000) Regulation of cytokinesis by the Elm1 protein kinase in Saccharomyces cerevisiae. J Cell Sci 113 ( Pt 8)():1435-45 SGD PMID 10725226
- ↑ Garrett JM (1997) The control of morphogenesis in Saccharomyces cerevisiae by Elm1 kinase is responsive to RAS/cAMP pathway activity and tryptophan availability. Mol Microbiol 26(4):809-20 SGD PMID 9427410
- ↑ Koehler CM and Myers AM (1997) Serine-threonine protein kinase activity of Elm1p, a regulator of morphologic differentiation in Saccharomyces cerevisiae. FEBS Lett 408(1):109-14 SGD PMID 9180279
- ↑ Sreenivasan A and Kellogg D (1999) The elm1 kinase functions in a mitotic signaling network in budding yeast. Mol Cell Biol 19(12):7983-94 SGD PMID 10567524
- ↑ Thomas CL, et al. (2003) Assembly interdependence among the S. cerevisiae bud neck ring proteins Elm1p, Hsl1p and Cdc12p. Yeast 20(9):813-26 SGD PMID 12845607
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-27
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