YLR299W
(Redirected from CIS2)
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| Systematic name | YLR299W |
| Gene name | ECM38 |
| Aliases | CIS2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:726069..728051 |
| Primary SGDID | S000004290 |
Description of YLR299W: Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation[1][2][3][4]
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in nitrogen limited chemostat cultures versus nitrogen excess. [5] [6]
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References
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- ↑ Kumar C, et al. (2003) Investigations into the polymorphisms at the ECM38 locus of two widely used Saccharomyces cerevisiae S288C strains, YPH499 and BY4742. Yeast 20(10):857-63 SGD PMID 12868055
- ↑ Kumar C, et al. (2003) Utilization of glutathione as an exogenous sulfur source is independent of gamma-glutamyl transpeptidase in the yeast Saccharomyces cerevisiae: evidence for an alternative gluathione degradation pathway. FEMS Microbiol Lett 219(2):187-94 SGD PMID 12620619
- ↑ Springael JY and Penninckx MJ (2003) Nitrogen-source regulation of yeast gamma-glutamyl transpeptidase synthesis involves the regulatory network including the GATA zinc-finger factors Gln3, Nil1/Gat1 and Gzf3. Biochem J 371(Pt 2):589-95 SGD PMID 12529169
- ↑ Ubiyvovk VM, et al. (2006) Role of gamma-glutamyltranspeptidase in detoxification of xenobiotics in the yeasts Hansenula polymorpha and Saccharomyces cerevisiae. Cell Biol Int 30(8):665-71 SGD PMID 16857395
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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