YPR173C

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Systematic name YPR173C
Gene name VPS4
Aliases CSC1, DID6, END13, GRD13, VPL4, VPT10
Feature type ORF, Verified
Coordinates Chr XVI:887833..886520


Description of YPR173C: AAA-type ATPase required for efficient late endosome to vacuole transport; catalyzes the release of an endosomal membrane-associated class E VPS protein complex; regulates cellular sterol metabolism; cytoplasmic and endosomal localization[1][2][3]




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References

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  1. Wang P, et al. (2005) AAA ATPases regulate membrane association of yeast oxysterol binding proteins and sterol metabolism. EMBO J 24(17):2989-99 SGD PMID 16096648
  2. Kumar A, et al. (2002) Subcellular localization of the yeast proteome. Genes Dev 16(6):707-19 SGD PMID 11914276
  3. Babst M, et al. (1998) The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function. EMBO J 17(11):2982-93 SGD PMID 9606181

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