YPR032W

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Systematic name YPR032W
Gene name SRO7
Aliases SNI1, SOP1
Feature type ORF, Verified
Coordinates Chr XVI:634120..637221


Description of YPR032W: Putative effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro77p and Drosophila lgl tumor suppressor[1][2][3][4]




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References

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  1. Grosshans BL, et al. (2006) The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p. J Cell Biol 172(1):55-66 SGD PMID 16390997
  2. Wadskog I, et al. (2004) Yeast lacking the SRO7/SOP1-encoded tumor suppressor homologue show increased susceptibility to apoptosis-like cell death on exposure to NaCl stress. Mol Biol Cell 15(3):1436-44 SGD PMID 14718573
  3. Larsson K, et al. (1998) The Saccharomyces cerevisiae SOP1 and SOP2 genes, which act in cation homeostasis, can be functionally substituted by the Drosophila lethal(2)giant larvae tumor suppressor gene. J Biol Chem 273(50):33610-8 SGD PMID 9837945
  4. Lehman K, et al. (1999) Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9. J Cell Biol 146(1):125-40 SGD PMID 10402465

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