Difference between revisions of "YPR024W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YPR024W YPR024W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006228 YPR024W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YME1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YME1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XVI:610478..612721
 
|nowrap| Chr XVI:610478..612721
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000006228
 
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'''Description of {{PAGENAME}}:''' Subunit, with Mgr1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover<ref name='S000113568'>Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 {{SGDpaper|S000113568}} PMID 16267274</ref><ref name='S000061539'>Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 {{SGDpaper|S000061539}} PMID 10192337</ref><ref name='S000051105'>Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 {{SGDpaper|S000051105}} PMID 9683639</ref><ref name='S000047590'>Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8
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'''Description of YPR024W:''' Subunit, with Mgr1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover<ref name='S000113568'>Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 {{SGDpaper|S000113568}} PMID 16267274</ref><ref name='S000061539'>Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 {{SGDpaper|S000061539}} PMID 10192337</ref><ref name='S000051105'>Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 {{SGDpaper|S000051105}} PMID 9683639</ref><ref name='S000047590'>Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8
 
  {{SGDpaper|S000047590}} PMID 8514129</ref>
 
  {{SGDpaper|S000047590}} PMID 8514129</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:46, 27 February 2007

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Systematic name YPR024W
Gene name YME1
Aliases OSD1, YTA11
Feature type ORF, Verified
Coordinates Chr XVI:610478..612721
Primary SGDID S000006228


Description of YPR024W: Subunit, with Mgr1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover[1][2][3][4]




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References

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  1. Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
  2. Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 SGD PMID 10192337
  3. Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 SGD PMID 9683639
  4. Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 SGD PMID 8514129

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