Difference between revisions of "YPR024W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006228 YPR024W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000006228 YPR024W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YME1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''YME1 ''

Revision as of 07:45, 23 January 2012

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Systematic name YPR024W
Gene name YME1
Aliases OSD1, YTA11
Feature type ORF, Verified
Coordinates Chr XVI:610481..612724
Primary SGDID S000006228


Description of YPR024W: Catalytic subunit of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover[1][2][3][4]




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References

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  1. Campbell CL and Thorsness PE (1998) Escape of mitochondrial DNA to the nucleus in yme1 yeast is mediated by vacuolar-dependent turnover of abnormal mitochondrial compartments. J Cell Sci 111 ( Pt 16)():2455-64 SGD PMID 9683639
  2. Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
  3. Leonhard K, et al. (1999) Chaperone-like activity of the AAA domain of the yeast Yme1 AAA protease. Nature 398(6725):348-51 SGD PMID 10192337
  4. Thorsness PE and Fox TD (1993) Nuclear mutations in Saccharomyces cerevisiae that affect the escape of DNA from mitochondria to the nucleus. Genetics 134(1):21-8 SGD PMID 8514129

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