YPR018W

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Systematic name YPR018W
Gene name RLF2
Aliases CAC1
Feature type ORF, Verified
Coordinates Chr XVI:594473..596293
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Description of YPR018W: Largest subunit (p90) of the Chromatin Assembly Complex (CAF-I) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin[1][2]



Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]


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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]


References

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  1. Glowczewski L, et al. (2004) Yeast chromatin assembly complex 1 protein excludes nonacetylatable forms of histone H4 from chromatin and the nucleus. Mol Cell Biol 24(23):10180-92 SGD PMID 15542829
  2. Adams CR and Kamakaka RT (1999) Chromatin assembly: biochemical identities and genetic redundancy. Curr Opin Genet Dev 9(2):185-90 SGD PMID 10322140
  3. 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. 4.0 4.1 submitted by Jeff Ubersax on 2004-01-29

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