YPR006C
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| Systematic name | YPR006C | |
| Gene name | ICL2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr XVI:568993..567266 | |
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Description of YPR006C: 2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol[1][2]
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References
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- ↑ Luttik MA, et al. (2000) The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism. J Bacteriol 182(24):7007-13 SGD PMID 11092862
- ↑ Heinisch JJ, et al. (1996) Molecular genetics of ICL2, encoding a non-functional isocitrate lyase in Saccharomyces cerevisiae. Yeast 12(13):1285-95 SGD PMID 8923733
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